• Product NameMCPH1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB;IHC;IF
• Species ReactivityHuman,Mouse
• SpecificityThe antibody detects endogenous level of total MCPH1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionThe antiserum was produced against synthesized peptide derived from human MCPH1
• Target NameMCPH1
• Alternative Names    MCT; BRIT1;
• Accession No. Swiss-Prot:Q8NEM0
  NCBI Gene ID:79648
• UniprotQ8NEM0
• Gene ID79648;
• SDS-PAGE MW 93KD
• Concentration 1.0mg/ml
• Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Storage Store at -20˚C

• WB 1:500-1:2000;
  IHC 1:100-1:300;
  IF 1:50-200

This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

• Western blot analysis of the lysates from HT-29 cells using MCPH1 antibody.
• Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting