• Product NameTAL-1 (Ab-122) Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total TAL-1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized non-phosphopeptide derived from human TAL-1 around the phosphorylation site of serine 122 (Q-L-S(p)-P-P).
• Target NameTAL-1
• Alternative Names    T-cell acute lymphocytic leukemia protein 1; SCL; TCL5;
• Accession No. Swiss-Prot: P17542
  NCBI Gene ID: 6886
• UniprotP17542
• Gene ID6886;
• SDS-PAGE MW 45kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation By similarity.

Aplan P.D., Mol. Cell. Biol. 10:6426-6435(1990).
Gregory S.G., Nature 441:315-321(2006).
Chen Q., J. Exp. Med. 172:1403-1408(1990)

• Western blot analysis of extracts from Jurkat cells, treated with PMA (125ng/ml, 30mins), using TAL-1 (Ab-122) antibody #33295.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting