• Product NameCD11c Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total CD11c protein.
• Immunogen TypePeptide-KLH
• Immunogen DescriptionPeptide sequence around aa.1155~1159(Q-T-P-S-P)derived from Human CD11c.
• Target NameCD11c
• Alternative Names    SLEB6; ITGAX;
• Accession No. Swiss-Prot: P20702
  NCBI Protein: NP_000878.2
• UniprotP20702
• Gene ID3687;
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

• Predicted MW: 145kd
  Western blotting: 1:500~1:1000
  

Integrin a-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.J. Proteome Res. 8:651-661(2009)

• Western blot analysis of extract from JK, HL-60 cells using CD11c Antibody #21491

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting