• Product NameARG2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ARG2 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from C-terminal of human ARG2.
• Target NameARG2
• Alternative Names    Arginase-2 mitochondrial; Arginase II; Non-hepatic arginase; Kidney-type arginase;
• Accession No. Swiss-Prot: P78540
  NCBI Gene ID: 384
• UniprotP78540
• Gene ID384;
• SDS-PAGE MW 38kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.

Gotoh T., FEBS Lett. 395:119-122(1996).
Vockley J.G., Genomics 38:118-123(1996).
Morris S.M. Jr., Gene 193:157-161(1997)

• Western blot analysis of extracts from HeLa cells, A549 cells, COLO205 cells and K562 cells, using ARG2 antibody #34438.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting