• Product NameAPOE Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total APOE protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from C-terminal of human APOE.
• Target NameAPOE
• Alternative Names    AD2; Apo-E; APOE; Apolipoprotein E; apolipoprotein E3
• Accession No. Swiss-Prot: P02649
  NCBI Gene ID: 348
• UniprotP02649
• Gene ID348;
• SDS-PAGE MW 36kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.

Zannis V.I., J. Biol. Chem. 259:5495-5499(1984).
McLean J.W., J. Biol. Chem. 259:6498-6504(1984).
Paik Y.-K., Proc. Natl. Acad. Sci. U.S.A. 82:3445-3449(1985).

• Western blot analysis of extracts from K562 cells, using APOE antibody #35301.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting