• Product NameMSH2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by antigen-affinity chromatography.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total MSH2 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionA synthesized peptide of human Angiopoietin 2
• Target NameMSH2
• Alternative Names    COCA1 antibody; FCC1 antibody; HNPCC antibody; HNPCC1 antibody; LCFS2 antibody; MSH2 antibody; DNA mismatch repair protein Msh2 antibody; mutS protein homolog 2 antibody; hMSH2 antibody; "mutS homolog 2; colon cancer; nonpolyposis type 1 (E. coli) antibod
• Accession No. Swiss-Prot#:P43246;
  NCBI Gene#:4436
• UniprotP43246
• Gene ID4436;
• SDS-PAGE MW 105kd
• Concentration 1mg/ml
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
   

MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq]

• Western blot analysis of extracts of various celllines, using MSH2 antibody.The lane on the left is treated with the antigen-specific peptide.
• Western blotting analysis using MSH2 Antibody #35358.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting