• Product NameINSIG2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total INSIG2 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to a region derived from internal residues of human insulin induced gene 2
• Target NameINSIG2
• Alternative Names    INSI2;INSIG2 membrane protein; insulin induced protein 2
• Accession No. Swiss-Prot#: Q9Y5U4
  NCBI Gene ID: 51141
  Gene Accssion: BC022475
• UniprotQ9Y5U4
• Gene ID51141;
• Concentration 1.4mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.

• Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #36556 at dilution 1/30.
• Immunohistochemical analysis of paraffin-embedded Human brain tissue using #36556 at dilution 1/30.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting